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Chia-Jui Yen Selected Research

alpha-Fetoproteins (alpha-Fetoprotein)

12/2022Ramucirumab as second-line treatment in Chinese patients with advanced hepatocellular carcinoma and elevated alpha-fetoprotein after sorafenib (REACH-2 China): A randomised, multicentre, double-blind study.
2/2022Safety of ramucirumab treatment in patients with advanced hepatocellular carcinoma and elevated alpha-fetoprotein.
1/2022Alpha-Fetoprotein as a Potential Surrogate Biomarker for Atezolizumab + Bevacizumab Treatment of Hepatocellular Carcinoma.
9/2021Ramucirumab for Patients with Intermediate-Stage Hepatocellular Carcinoma and Elevated Alpha-Fetoprotein: Pooled Results from Two Phase 3 Studies (REACH and REACH-2).
1/2021Serum alpha-fetoprotein and clinical outcomes in patients with advanced hepatocellular carcinoma treated with ramucirumab.
8/2020Efficacy and Safety of Ramucirumab in Asian and Non-Asian Patients with Advanced Hepatocellular Carcinoma and Elevated Alpha-Fetoprotein: Pooled Individual Data Analysis of Two Randomized Studies.
3/2018Progesterone receptor membrane component 1 as a potential prognostic biomarker for hepatocellular carcinoma.
1/2018Alpha-fetoprotein kinetics in patients with hepatocellular carcinoma receiving ramucirumab or placebo: an analysis of the phase 3 REACH study.
2/2015Sgo1 is a potential therapeutic target for hepatocellular carcinoma.

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Chia-Jui Yen Research Topics

Disease

67Neoplasms (Cancer)
01/2024 - 04/2008
53Hepatocellular Carcinoma (Hepatoma)
10/2023 - 07/2011
15Adenocarcinoma
03/2024 - 04/2008
14Neoplasm Metastasis (Metastasis)
10/2023 - 08/2011
13Head and Neck Neoplasms (Head and Neck Cancer)
01/2021 - 11/2011
10Squamous Cell Carcinoma of Head and Neck
03/2024 - 10/2017
8Stomach Neoplasms (Stomach Cancer)
01/2023 - 01/2014
8Hypertension (High Blood Pressure)
12/2022 - 07/2015
7Carcinogenesis
01/2018 - 04/2008
6Pancreatic Neoplasms (Pancreatic Cancer)
03/2024 - 05/2020
6Disease Progression
11/2023 - 07/2015
6Liver Neoplasms (Liver Cancer)
02/2023 - 07/2015
6Inflammation (Inflammations)
08/2021 - 04/2008
4Nasopharyngeal Carcinoma
11/2023 - 10/2014
4Fatigue
12/2021 - 12/2014
4Neutropenia
10/2020 - 03/2016
4Breast Neoplasms (Breast Cancer)
09/2020 - 08/2008
4Pain (Aches)
04/2020 - 01/2017
4Nausea
12/2019 - 12/2014
4Infections
07/2015 - 02/2004
3Fibrosis (Cirrhosis)
12/2021 - 02/2017
3Cancer Pain
04/2020 - 01/2017
3Diarrhea
12/2019 - 12/2014
3Vomiting
12/2019 - 12/2014
3Liver Diseases (Liver Disease)
01/2019 - 07/2015
3Exanthema (Rash)
05/2018 - 12/2014
3Chronic Hepatitis B
05/2016 - 01/2012
2Esophageal Squamous Cell Carcinoma
06/2023 - 03/2015
2Pneumonia (Pneumonitis)
12/2022 - 01/2020
2Hepatitis C
12/2021 - 02/2004
2Pruritus (Itching)
12/2021 - 10/2017
2Hemorrhage
01/2021 - 12/2020
2Febrile Neutropenia
12/2020 - 03/2018
2Asthenia
08/2020 - 07/2015
2Ascites
08/2020 - 07/2015
2Obesity
05/2020 - 11/2008
2Hematologic Neoplasms (Hematological Malignancy)
01/2020 - 08/2019
2Leukopenia
03/2018 - 03/2016
2Carcinoma (Carcinomatosis)
01/2017 - 12/2016
2Hypoxia (Hypoxemia)
02/2016 - 10/2015
2Hypersensitivity (Allergy)
01/2016 - 01/2013

Drug/Important Bio-Agent (IBA)

17RamucirumabIBA
12/2022 - 07/2015
14Biomarkers (Surrogate Marker)IBA
03/2024 - 07/2011
13Sorafenib (BAY 43-9006)FDA Link
12/2022 - 08/2008
12Fluorouracil (Carac)FDA LinkGeneric
03/2024 - 08/2011
11GemcitabineFDA Link
03/2024 - 01/2020
11Leucovorin (Folinic Acid)FDA Link
03/2024 - 01/2014
10Irinotecan (Camptosar)FDA LinkGeneric
03/2024 - 01/2020
9alpha-Fetoproteins (alpha-Fetoprotein)IBA
12/2022 - 02/2015
7Cisplatin (Platino)FDA LinkGeneric
11/2023 - 01/2014
7Messenger RNA (mRNA)IBA
09/2023 - 01/2013
7Paclitaxel (Taxol)FDA LinkGeneric
08/2021 - 08/2008
5MicroRNAs (MicroRNA)IBA
09/2023 - 04/2013
5PlatinumIBA
12/2021 - 03/2016
5Proteins (Proteins, Gene)FDA Link
01/2020 - 08/2008
4Cetuximab (Erbitux)FDA Link
02/2024 - 01/2019
4NivolumabIBA
10/2023 - 10/2017
4ErbB Receptors (EGF Receptor)IBA
10/2023 - 04/2013
4Bevacizumab (Avastin)FDA Link
12/2022 - 08/2011
4BilirubinIBA
09/2021 - 07/2015
4Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2021 - 12/2014
4Analgesics (Analgesic Drugs)IBA
04/2020 - 01/2017
4CytokinesIBA
06/2019 - 11/2008
4Phosphotransferases (Kinase)IBA
04/2013 - 04/2008
3toripalimabIBA
11/2023 - 01/2021
3Monoclonal AntibodiesIBA
10/2023 - 01/2016
3hepatitis B virus X proteinIBA
09/2023 - 01/2012
3Tyrosine Kinase InhibitorsIBA
01/2023 - 01/2011
3Cadherins (E-Cadherin)IBA
12/2022 - 01/2014
3atezolizumabIBA
12/2022 - 01/2022
3Membrane Proteins (Integral Membrane Proteins)IBA
05/2022 - 07/2015
3AlbuminsIBA
01/2022 - 04/2021
3DNA (Deoxyribonucleic Acid)IBA
12/2021 - 07/2015
3Fetal Proteins (Fetoprotein)IBA
01/2019 - 01/2014
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2015 - 08/2011
3Ribosomal Protein S6 Kinases (S6 Kinase)IBA
01/2012 - 04/2008
3TOR Serine-Threonine KinasesIBA
01/2012 - 04/2008
2AntigensIBA
09/2023 - 04/2014
2tislelizumabIBA
02/2023 - 01/2020
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
12/2022 - 12/2014
2spartalizumabIBA
06/2022 - 12/2021
2ADI PEG20IBA
12/2021 - 01/2021
2Oxaliplatin (Eloxatin)FDA LinkGeneric
12/2021 - 01/2019
2pembrolizumabIBA
06/2021 - 01/2021
2Metformin (Glucophage)FDA LinkGeneric
09/2020 - 01/2020
2CCAAT-Enhancer-Binding Protein-deltaIBA
01/2020 - 11/2015
2nintedanibIBA
05/2018 - 01/2017
2Sirolimus (Rapamycin)FDA Link
01/2018 - 04/2008
2Surface Antigens (Surface Antigen)IBA
01/2018 - 02/2013
2codrituzumabIBA
02/2017 - 01/2016
2SERPIN-B5 (maspin)IBA
08/2016 - 09/2015
2Lapatinib (GW572016)FDA Link
01/2016 - 04/2013
2Oncogene Proteins (Oncogene Protein)IBA
07/2015 - 02/2013

Therapy/Procedure

32Therapeutics
02/2024 - 02/2004
16Drug Therapy (Chemotherapy)
01/2024 - 08/2011
5Neoadjuvant Therapy
06/2023 - 10/2014
5Oral Hygiene (Dental Hygiene)
05/2020 - 10/2013
3Pain Management
04/2020 - 05/2019
2Radiotherapy
02/2023 - 10/2014
2Chemoradiotherapy
03/2015 - 10/2014